11-Epiisoeusantona-1,4-dienic acid, 6alpha-hydroxy-3-oxo-, gamma-lactone
Santonin
CAS: 481-06-1
Molecular Formula: C15H18O3
11-Epiisoeusantona-1,4-dienic acid, 6alpha-hydroxy-3-oxo-, gamma-lactone - Names and Identifiers
11-Epiisoeusantona-1,4-dienic acid, 6alpha-hydroxy-3-oxo-, gamma-lactone - Physico-chemical Properties
| Molecular Formula | C15H18O3 |
| Molar Mass | 246.3 |
| Density | 1.5900 |
| Melting Point | 172-173°C(lit.) |
| Boling Point | 329.3°C (rough estimate) |
| Specific Rotation(α) | -172.5 ° (C=2, CHCl3) |
| Water Solubility | 0.2g/L(17.5 ºC) |
| Solubility | Soluble in alcohol, ether, chloroform, alkali and most volatile oil and fatty oil, slightly soluble in water. |
| Appearance | Colorless rhombic wedge transparent crystal or white powder |
| Color | White to Off-White |
| Merck | 14,8361 |
| BRN | 89489 |
| Storage Condition | 2-8°C |
| Refractive Index | -172.5 ° (C=2, CHCl3 |
| MDL | MFCD00135865 |
| Physical and Chemical Properties | Colorless orthorhombic wedge-shaped transparent crystal or white powder. Melting point 170-173 ℃, relative density 1.187. Soluble in alcohol, ether, chloroform, alkali and most volatile oil and fatty oil, slightly soluble in water. Boiling point sublimation. Shined by light, gradually yellow. At first it is tasteless, then it turns bitter and poisonous. Shan Daowan is a ketolide containing two double bonds. After dissolving in alkali, it opens the lactone ring to form a salt, which is acidified and turned back to the original. |
11-Epiisoeusantona-1,4-dienic acid, 6alpha-hydroxy-3-oxo-, gamma-lactone - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed. |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S37 - Wear suitable gloves. S36 - Wear suitable protective clothing. S28 - After contact with skin, wash immediately with plenty of soap-suds. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| RTECS | LE3150000 |
| Hazard Class | 6.1(a) |
| Packing Group | II |
11-Epiisoeusantona-1,4-dienic acid, 6alpha-hydroxy-3-oxo-, gamma-lactone - Reference
| Reference Show more | 1. [IF=11.878] Li Xinming et al."A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage."Nat Commun. 2019 Jun;10(1):1-12 |
11-Epiisoeusantona-1,4-dienic acid, 6alpha-hydroxy-3-oxo-, gamma-lactone - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| biological activity | Santonin (Alpha-Santonin) is the active ingredient of artemsia cina and can be used to study helminth infection. |
| Use | anthelmintic. For Ascaris infection has been used for a long time, the effect is remarkable. |
| production method | , it can be extracted from the flower bud of Chrysanthemum morifolium. Take the flower buds of Artemisia selengensis, add milk of lime (pH11-12), soak and cook in hot water, neutralize the obtained leaching solution with hydrochloric acid, reduce the pressure and reduce the depth, cool down, and adjust the pH to 1-2 with hydrochloric acid, after stirring and heating, a cyclization solution was obtained. The cyclization liquid was sufficiently cooled to precipitate the annual crystals of the mountain track. The obtained crude product was recrystallized with ethanol to obtain the finished product of the mountain road year.
Last Update：2024-04-09 21:11:58
Supplier List
Spot supply
Product Name: Santonin Visit Supplier Webpage Request for quotationCAS: 481-06-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Santonin Visit Supplier Webpage Request for quotationCAS: 481-06-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History